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Jeng-Wei Lu

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Open access Sep 2026

Unveiling the antiviral mechanism of A4S7: a synthetic antimicrobial peptide targeting dengue and other mosquito-borne enveloped virus infections.

Dengue virus (DENV), an enveloped mosquito-borne flavivirus, is the causative agent of dengue and prevalent in tropical and subtropical regions. Severe cases can progress to dengue hemorrhagic fever or shock syndrome, posing significant public health challenges. In the absence of specific antiviral drugs, antimicrobial...

Ting-Chun Lin, Jeng-Wei Lu, Chia-Hsin Liu et al. · 0 citations
Open access Aug 2026

The Mechanism of Monolaurate Derived Glycolipids Inhibit Sindbis Virus Replication and Release

Investigation of the antiviral properties and underlying mechanism of trehalose 6‐monolaurate against Sindbis virus establishes TML as a host‐directed inhibitor acting at post‐entry stages of alphavirus replication and underscores its potential as a lead scaffold for the development of therapeutics against mosquito‐bor...

Jeng-Wei Lu, M. Helal, Guan-Chiun Lee et al. · 0 citations

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