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Author

Jenna Jones

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Open access Jul 2026

Zika Virus NS3 Drives the Assembly of a Replication Compartment-like Structure That Exerts the Structural and Physiological Functions of the Viral Replication Compartment

It is shown that the ZIKV non-structural protein 3 (NS3), a dual-function protease and RNA helicase, is sufficient to drive the assembly of a replication compartment-like structure (RCLS) in human cells, and that the helicase domain and not the protease domain is required for optimal RCLS formation and organelle recrui...

T. Sultana, Chunfeng Zheng, Jenna Jones et al. · 0 citations

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