Jenna R. Valley

An atlas of the C. elegans starvation response reveals that transcription is necessary to initiate transcriptional silencing in quiescent primordial germ cells

Starvation profoundly impacts development, but how different tissues respond to starvation is unclear. We generated a cellular atlas of gene expression in fed and starved C. elegans L1 larvae. We identified 79 cell types in both conditions, and we detected ∼98% of protein-coding genes, 44% of which were differentially...