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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Jennifer L Anderson

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2 papers indexed here

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Sep 2026

Abstract B083: Mutant KRAS cooperates with the hypoxic tumor microenvironment to drive immunosuppressive macrophages via a paracrine PGE2/GM-CSF axis

Hypoxia is known to drive an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma (PDAC). However, the underlying immunosuppressive mechanisms remain unclear. Here, we hypothesized that hypoxia-induced factors secreted from tumor cells promoted immunosuppressive macrophages in PDAC. We tr...

Matthew T. Cribb, Ayeisha N. Colón-Ortiz, Sahar Fattani et al. · 0 citations
Aug 2026

Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer.

Overall immune-cell composition was largely preserved despite differences in immune-cell distribution, spatial organization, and T cell clonality, and multi-cohort validation across complementary spatial and single-cell platforms identified consistent alterations in innate-adaptive immune organization in immunosuppress...

Shorook Naara, V. Kochat, Xiayu Rao et al. · 1 citation

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