Open access
Aug 2026
46 Anti-tumour immune responses in melanoma brain metastases require cDC1 population and the extracranial tumour
It is hypothesize that extracranial tumour inhibits intracranial tumour growth through extracranial cDC1-mediated priming and expansion of CD8+ T cells which then home to intracranial tumours, by directly enhancing the activation of intracranial cDC1s, or a combination of both.
Dario Guglietta, Alca Revalova, Fiona R. James et al.
· Neuro-Oncology · 0 citations