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Jeong Hyun Lee

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Open access Sep 2026

KR-36996, an orally active urotensin II receptor antagonist, attenuates hepatic inflammation and fibrosis in methionine- and choline-deficient diet-induced fibrosing steatohepatitis.

Metabolic dysfunction-associated steatohepatitis (MASH), a progressive form of metabolic dysfunction-associated steatotic liver disease, is characterized by hepatocellular injury, chronic inflammation, and fibrosis, yet effective antifibrotic therapies remain limited. The urotensin II (UII)/urotensin II receptor (UTR)...

Yeong-Cheol Han, Seung Hyeong Lee, Seoha Lee et al. · 0 citations

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