Author

Jeong-Sun Kim

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Open access Aug 2026

Host nucleolin-targeting unique peptide drugs as potent broad-spectrum anti-influenza therapies

AGM-380d and AGM-380t are highly promising as novel, broad-spectrum host-directed antivirals for the management of seasonal and pandemic influenza.

Thu Ha Nguyen, Muhammad Sharif, Jae-hyun Kim et al. · PNAS Nexus · 0 citations

Aug 2026

Structural landscape of a wide-open TPP: Insights into extreme conformational plasticity and allosteric potential.

The biochemical and structural characterization of Dermatophilus congolensis TPP is reported, which reveals a moderate catalytic turnover consistent with other bacterial orthologs and suggests a cryptic allosteric site that can be targeted to lock the enzyme in an inert state.

San Kim, Karthik Rajan Rajamanickam, H.-G. Woo et al. · Biochemical and Biophysical... · 0 citations