Open access
Jul 2026
FUS-driven zebrafish model of ALS identifies tribenzylamine as a candidate modulator of ALS-associated pathology.
Findings support the mtFUS zebrafish model as a useful platform for ALS drug discovery and identify tribenzylamine as a candidate modulator of ALS-associated phenotypes, with effects linked to transcriptomic remodeling and neuronally active sex steroid signaling.
Yongbo Seo, Jeonghyeon Lee, Yunkyoung Lee et al.
· Biomedicine & pharmacotherap... · 0 citations