Author

Jeremy D. Kratz

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Sep 2026

Abstract B021: Epigenetic Reprogramming of Intraductal Papillary Mucinous Neoplasms (IPMNs) by Pancreatic Cancer Associated Fibroblasts

Intraductal papillary mucinous neoplasms (IPMNs) are established precursors to pancreatic ductal adenocarcinoma (PDAC). While IPMNs are the only pancreatic precursor readily identified by clinical imaging, no tools readily predict progression to cancer. The local pancreatic tumor microenvironment (TME) is heavily...

Hailee I. Porter, M. S. Hossan, Timothy Hoggard et al. · Cancer Research · 0 citations

Open access Jul 2026

Long-read, whole-genome sequencing and chemotherapy response of two patient-derived organoids from a TP53- and KRAS-mutant ovarian carcinoma

Two PDOs with differential responses to carboplatin derived from sequential ascites fluid collections from a patient with high-grade müllerian carcinoma are described and the ability of long-read sequencing to add detail into the genomics and epigenetics of ovarian cancer is demonstrated.

J. Wendt, Kristin M. Adams, Ryan Moreno et al. · bioRxiv · 0 citations