Crosstalk between NUAK1 and the SETD1A complex regulates glycolysis and gluconeogenesis upon glucose deprivation.
Glucose is a crucial energy source, and glucose metabolism represents central chemical reactions in redox homeostasis. We previously found that histone H3 threonine 11 phosphorylation (H3pT11), which requires histone H3 lysine 4 trimethylation (H3K4me3), promotes the transcription of genes regulating mitochondrial resp...