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Author

Jesper L. Kristensen

2 papers indexed here

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Open access Sep 2026

Exploring a Druggable Hydrophobic Tunnel in the 5-HT2A Receptor with Potent Phenethylamines

The serotonin 2A receptor is the most abundant excitatory serotonin receptor in the brain and the target for serotonergic psychedelics. Despite its importance, the mechanisms of action and structure−activity relationship of receptor agonists are not fully understood. Experimental 5-HT2AR structures have identified a...

Icaro A. Simon, Eline Pottie, Madeleine K. Jensen et al. · 2 citations · ⚡1

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