Abstract A028: Metastatic potential defines an orthogonal axis of transcriptomic heterogeneity that predicts chemotherapy response and tumor microenvironment architecture in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) has traditionally been classified into two overarching transcriptomic subtypes—classical and basal—which have been associated with distinct clinical behaviors and therapeutic responses. We recently identified a previously unrecognized transcriptomic axis governing metastati...