Open access
Oct 2026
Spatiotemporal co-regulation of IL2 and TCR receptors reveals early antigen-driven synaptic synergy in human CD8+ T cells
It is shown that TCR and IL2 signaling overlap in space and time and synergize when simultaneously triggered, demonstrating synergistic TCR and IL2R signaling that drives efficient expansion of antigen-specific CD8 + T cells.
Jesusa Capera, María Navarro-Pérez, Ashwin K. Jainarayanan et al.
· Nature Communications · 0 citations