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Sep 2026
Background The effect of sodium–glucose cotransporter-2 inhibitors (SGLT2i) in patients with left ventricular assist devices (LVAD) remains uncertain. We evaluated the association between SGLT2i use and adverse outcomes during the chronic post-LVAD phase. Methods We conducted a retrospective cohort study using the TriN...
Jheng-Yan Wu, Keng-Wei Lee, Sheng-Chi Huang et al.
· Frontiers in Pharmacology · 0 citations
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Sep 2026
AIM
To evaluate whether the use of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) is associated with a reduced 1-year incidence of new-onset heart failure (HF) compared to statins among patients with dyslipidemia.
METHODS
We conducted a retrospective cohort study using the TriNetX global health re...
Jheng-Yan Wu, Keng-Wei Lee, Sheng-Chi Huang et al.
· QJM : monthly journal of the... · 0 citations
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Open access
Sep 2026
Background Atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis (AS) share lipid-related mechanisms. Although statins have not slowed established AS progression in randomized trials, whether proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) are associated with lower incident AS risk remai...
Jheng-Yan Wu, Keng-Wei Lee, Sheng-Chi Huang et al.
· JACC: Advances · 0 citations
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Aug 2026
BACKGROUND
Chronic obstructive pulmonary disease (COPD) is frequently complicated by acute respiratory failure, pneumonia, exacerbations, and premature mortality, particularly in patients with comorbid type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) possess anti-inflammatory and metabolic pr...
Kuang-Ming Liao, Ya-Wen Tsai, K. Kostikas et al.
· QJM : monthly journal of the... · 0 citations
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