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Author

Ji-Feng Zhang

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Jul 2026

PTEN Negatively Regulates Spastin Ser210 Phosphorylation To Modulate GluA1 Surface Trafficking and Excitatory Synaptic Transmission.

This research indicates that PTEN is the pathway that regulates the phosphorylation of spastin, providing an important reference for the treatment of neurological diseases characterized by microtubule dysregulation.

Dan-Lei Liu, Jiagui Zhong, Lai-Jian Wang et al. · 0 citations
Open access Jul 2026

Social isolation disrupts prefrontal excitatory-inhibitory balance to impair social novelty memory in adult male mice.

It is established that adult social isolation disrupts social novelty memory processing by shifting the mPFC excitatory-inhibitory balance toward a net hyperexcitable state, revealing a reversible, circuit-specific mechanism for isolation-induced social cognitive deficits.

Quan Yuan, Bing-Yu Ren, Laijian Wang et al. · 1 citation

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