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Author

Ji-Gang Piao

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Review Open access Oct 2026

Plant essential oils as a novel therapeutic strategy for depression and anxiety: emerging evidence and mechanisms

Depression and anxiety are major global mental health disorders that require safer and more accessible adjunctive interventions. This review uniquely integrates current evidence on plant essential oils in aromatherapy and identifies the cAMP–PKA–CREB pathway as a key mechanistic hub linking neurotransmitter regulation,...

Jia-Hui Hong, Li-Ting He, Jing-Quan Chen et al. · 0 citations
Open access Aug 2026

Reprogramming PD-L1 endosomal recycling and lysosomal degradation via engineered exosome-based nanocomposites overcomes immune resistance in lung cancer brain metastasis

A pH-responsive nanocomposite engineered by functionalizing brain-metastatic tumor cell-derived exosomes with RGD peptides for targeted co-delivery of verteporfin and αPD-L1 successfully remodels the intracranial immunosuppressive microenvironment and triggers potent systemic anti-tumor immunity.

Xiujuan Hong, Xiao-Qi Wang, Wan-Kun Wang et al. · 0 citations

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