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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ji-Shan Li

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Sep 2026

Structure-Guided Stepwise Engineering of a Microbial Glycosyltransferase for Highly Regioselective and Efficient Biosynthesis of Salidroside

Uridine diphosphate glycosyltransferases (UGTs) are among the key rate-limiting enzymes in the biosynthesis of salidroside. Plant-derived UGTs often exhibit poor solubility and low catalytic activity, whereas microbial UGTs typically show insufficient regioselectivity for salidroside production. In this study, we per...

Mu-Yang Li, Yi-Wei Meng, Ji-Shan Li et al. · 0 citations

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