PI3K/AKT signaling contributes to prenatal nicotine exposure-induced developmental impairment of the pontomedullary respiratory network in neonatal rats.
Prenatal nicotine exposure (PNE) disrupts the development of the pontomedullary respiratory network and increases susceptibility to respiratory dysfunction after birth. However, the role of PI3K/AKT signaling in PNE-induced impairment of neuronal development within the pontomedullary respiratory network remains unclear...