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Author

Ji-Yang Zhang

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Sep 2026

Drug−Drug Salts of Rucaparib with Nonsteroidal Anti-Inflammatory Drugs: Crystal Structures, Intermolecular Interactions, Solubility Enhancement, and Antitumor Activity

Rucaparib (RUCA) is an orally administered PARP inhibitor with an important clinical value in cancer therapy, but its poor aqueous solubility remains a major challenge for improving its dissolution behavior and pharmaceutical performance. In this study, drug−drug salt formation was adopted to improve the physicochemi...

Can Wang, Shuo Liu, Ji-Yang Zhang et al. · 0 citations

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