Open access
Aug 2026
Integrative multi-omics identifies PANX2 as a ferroptosis suppressor and potential therapeutic target in clear cell renal cell carcinoma
PANX2 is identified as a ccRCC-relevant suppressor of ferroptosis and supports the involvement of a PANX2-Akt/mTOR-SLC7A11-associated signaling axis in redox homeostasis and tumor progression.
Xing-Lin Li, Yiqi Xiong, Ji-Yin Wang et al.
· Frontiers in Immunology · 0 citations