Ji-Yong Meng

Cyclometalated iridium complex with red-light activation for dual ferroptosis-apoptosis cancer therapy.

Conventional cancer therapies such as chemotherapy primarily rely on apoptosis induction; however, their efficacy is often compromised by the development of apoptosis resistance in tumor cells. A new cyclometalated iridium complex, IrOAc, was designed and synthesized in this study. Its improved red-light absorption in...