Neonatal mortality risk prediction from bedside monitoring data remains challenging due to extreme class imbalance, heterogeneous clinical risk factors, multi-scale temporal dynamics, and substantial missingness. We propose NeoTriFuse, a reliability-aware multimodal fusion framework for missingness-heterogeneous neonatal monitoring data. Unlike conventional multimodal approaches that treat missingness primarily as a preprocessing issue, NeoTriFuse models missingness as an explicit reliability signal that dynamically modulates modality contributions during fusion. The framework integrates static perinatal variables, local-global temporal encoders, and patient-level statistical summaries through reliability-guided gating mechanisms, while jointly optimizing mortality prediction and an auxiliary length-of-stay objective. NeoTriFuse achieves competitive performance, with an F1 score of 0.6736 +/- 0.0216 and an AUROC of 0.9454 +/- 0.0056. Ablation studies indicate that the local-global temporal architecture and patient-level summary branch contribute most substantially to predictive performance, while reliability-aware gating provides additional improvements on threshold-dependent metrics under heterogeneous observation completeness. Sensitivity analyses further suggest stable performance across nearby hyperparameter settings. Overall, the findings support reliability-aware multimodal fusion as a practical approach for neonatal mortality prediction under realistic clinical missingness conditions.
Graph neural networks (GNNs) can exhibit unfair behavior even when sensitive attributes are excluded from node features, because graph topology and message passing propagate group-correlated signals under sensitive homophily. Existing fairness-aware GNN methods mainly constrain representations or prediction distributions at a global level, without explicitly controlling the local structural pathways through which biased information propagates during aggregation. We propose Subgraph Filtering for Fair Graph Neural Networks (SF-GNN), a lightweight and architecture-agnostic framework that mitigates structural bias at its source. SF-GNN identifies bias-prone edges by combining sensitive homophily with structural propagation amplifiers, including hub participation and triadic closure. It then incorporates stochastic edge filtering into each message-passing step to selectively downweight or remove these edges while preserving the remaining graph structure. Training further incorporates a statistical-parity regularizer with a warm-up schedule to stabilize optimization. Experiments on five benchmark datasets show that SF-GNN achieves consistent fairness improvements while maintaining competitive predictive performance, leading to a better fairness--accuracy trade-off than recent fairness-aware GNN baselines.
Haohui Lu, Ji-Yuan Tian, Fangyu Zhou et al.· 0 citations