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Author

Jiabao Liu

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Open access Sep 2026

The nematode Caenorhabditis elegans has a cationic amphiphilic drug (CAD) defense system

Cationic Amphiphilic Drugs (CADs) severely disrupt lysosomal function, which leads to a cellular pathology in humans characterized by excess phospholipids called phospholipidosis. Through a forward genetic screen and mining of published datasets, we discovered that CADs induce the expression of the CYP-35B family of cy...

Levon Tokmakjian, Duhyun Han, Kateryna Sihuta et al. · 0 citations
Open access Aug 2026

Asiatic acid remodels the gastric precancerous immune microenvironment by targeting STING

Collectively, AA interrupts the vicious “microbiota–oxidative stress–STING” loop in a STING‑dependent manner and contributes to remodeling the precancerous immune microenvironment, positioning it as a promising chemopreventive candidate targeting the earliest phase of gastric carcinogenesis.

Hao-Tian Li, Li Shen, Jia-Bao Liu et al. · 0 citations

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