Author

Jia-Cheng Wang

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Open access Sep 2026

Neutrophil percentage-to-albumin ratio and in-hospital mortality after emergency repair of ruptured abdominal aortic aneurysm: a retrospective cohort study

Rupture is the most catastrophic presentation of abdominal aortic aneurysm (AAA). Despite emergency repair, ruptured abdominal aortic aneurysm (RAAA) remains associated with high mortality, and prognosis is difficult to predict. This study examined whether admission neutrophil percentage-to-albumin ratio (NPAR) w...

Jia-Cheng Wang, Ru-Chen Li, Xue-Jun Wu · BMC Cardiovascular Disorders · 0 citations

Oct 2026

Histone lactylation-upregulated CEBPB transcriptionally activates CXCL12 and p21 to modulate vascular smooth muscle cell senescence and macrophage polarization.

BACKGROUND Abdominal aortic aneurysm (AAA) represents a widespread vascular disorder associated with high significant mortality rates, and the phenotypic transformation of vascular smooth muscle cells (VSMCs) acts as a crucial pathological characteristic during the advancement of this condition. Recent studies suggest...

Yong-Xin Han, Jia-Cheng Wang, Ru-Chen Li et al. · Cellular Signalling · 0 citations

Aug 2026

Hemodynamic Differences Associated With Extreme Versus Minimal Proximal Neck Angulation in Ruptured Infrarenal Abdominal Aortic Aneurysms: A Patient-Specific Computational Study.

BACKGROUND Maximum aneurysm diameter remains the principal criterion for abdominal aortic aneurysm (AAA) risk assessment, but additional morphologic and biomechanical factors may help explain the heterogeneity of rupture-related vulnerability. This exploratory study aimed to characterize hemodynamic differences associa...

Ru-Chen Li, Qing-Peng Song, Xiao-Han Wang et al. · Annals of Vascular Surgery · 0 citations