Author

Jia Fan

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Clinical trial Aug 2026

Liver resection after atezolizumab and bevacizumab versus maintenance therapy for locally advanced hepatocellular carcinoma (TALENTOP): a multicentre, open-label, randomised, phase 3 trial.

BACKGROUND Resection might offer additional benefit in patients with advanced-stage hepatocellular carcinoma treated with systemic therapy. However, high-quality evidence supporting the procedure is absent. We aimed to establish whether resection can provide survival benefit in patients with advanced hepatocellular car...

Hui-Chuan Sun, Xiao-Dong Zhu, Feng Shen et al. · The Lancet · 3 citations · ⚡1

Jul 2026

FGFR2 Fusion-Driven CXCL3 Downregulation Attenuates Neutrophil Recruitment in Intrahepatic Cholangiocarcinoma.

Mechanistic insights are provided into the paradox between the oncogenic properties of FGFR2 fusion and favorable clinical outcomes in FGFR2 fusion-positive iCCA, and a potential strategy to optimize FGFR2-targeted therapies is suggested.

Tao Zhu, Jia-Cheng Lu, Yan-Zi Pei et al. · Cancer Letters · 0 citations