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Author

Jia Guo

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Open access Sep 2026

Immunoinformatics-Guided Design, Immunological Evaluation, and Macrophage Transcriptomic Profiling of a Multi-Epitope Vaccine Candidate Against Mycobacterium avium subsp. paratuberculosis

Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease in ruminants and is difficult to control once persistent infection is established. We designed a MAP multi-epitope vaccine candidate by screening conserved proteins and assembling predicted B-cell, MHC class I-restricted cytotoxic T lymphocyte (CT...

Zhi-Jie Luo, Zeng-Ke Wei, Jia-Luo Xu et al. · 0 citations
Open access Aug 2026

Ability of Brucella melitensis 16M to Control Nitrogen Process: Identification of a Novel P-II Family Nitrogen Regulator

The genome-wide analysis revealed extensive FtcR-binding sites throughout the B. melitensis 16M genome, including the identification of glnB as a novel target, which suggests FtcR plays a direct role in modulating nitrogen, carbon, and energy metabolism under prolonged nutrient starvation.

Yi-Dan Zhang, Yu Zhang, Sheng-Nan Song et al. · 0 citations

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