Author

Jia Han

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Open access Oct 2026

Glyceraldehyde May Induce the Generation of High-Molecular-Weight Species of HSP90β and Autophagy-Related Proteins and Alter Protein Levels in Human Renal Epithelial Cells

Kidney disease (KD) is a major health problem, and metabolic disorders contribute to diabetic nephropathy and chronic kidney disease, in which renal epithelial cell dysfunction plays an important role. Intracellular advanced glycation end-products (AGEs) may contribute to KD progression by disrupting cellular homeostas...

Thanh Thao Nguyen, T. Takata, Shinya Inoue et al. · Biomolecules · 0 citations

Aug 2026

Integrated Spatial Immune Phenotyping Identifies a Suppressive-infiltrated High-risk Subgroup in Esophageal Squamous Cell Carcinoma

Background/Aim: Esophageal squamous cell carcinoma (ESCC) exhibits substantial heterogeneity in its tumor immune microenvironment (TIME). We aimed to establish an integrated spatial immune phenotyping framework incorporating immune infiltration, spatial distribution, and suppressive-effector immune balance. Patients an...

W. Jiao, Dan Wang, Jia Han et al. · Anticancer Research · 0 citations