Tetramethylpyrazine modulates the Nrf2/JNK axis to intervene in ferroptosis and neuroinflammation after spinal cord injury: an integrated perspective from antioxidant to regenerative therapy
The interplay between ferroptosis and neuroinflammation during secondary injury after spinal cord injury (SCI) critically drives permanent neurological dysfunction. Targeting both processes simultaneously is a promising therapeutic strategy. Tetramethylpyrazine (TMP), the main active component of Ligusticum chuanxiong,...