Author

Jia-He Qiu

2 papers indexed here

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Oct 2026

SAEKP: A Site Attention Enzyme Kinetics Prediction Method to Facilitate Enzyme Engineering

While the determination of enzyme kinetic parameters traditionally relies on prolonged and costly experimental methods, machine learning models have recently demonstrated promise as predictive tools. These models still have limitations, such as limited training data and insufficient sensitivity to mutations at import...

Jia-He Qiu, Zong-Ying Lin, Ke-Wei Chen et al. · Journal of Chemical Informat... · 0 citations

Sep 2026

A Sequence-to-Scaffold Platform Enables Programmable Carrier-Supported Biocatalysis for Nucleoside Analog Synthesis

Industrial biocatalysis increasingly requires strategies that convert enzyme discovery into robust catalyst systems for process implementation. Here, we report Spatially Programmable Assembly of Computationally Mined Enzymes (SPACE), a sequence-to-scaffold workflow coupling multiparametric enzyme mining with programm...

Qiang Wang, Teng Bao, Jia-He Qiu et al. · ACS Catalysis · 0 citations