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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jia-Heng Lin

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Open access Sep 2026

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

ABSTRACT Lung squamous cell carcinoma (LUSC) is a highly aggressive malignancy with a dismal prognosis and limited targeted therapies. While post‐translational and RNA modifications are implicated in tumor progression, their precise roles in LUSC remain elusive. Here, we identify the RNA methyltransferase FTSJ3 as a cr...

Qin Hu, Jia-Heng Lin, Yi-Fei Zhu et al. · 0 citations

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