Author

Jia-Hong Lu

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Aug 2026

Titanium dioxide nanoparticles induce neurotoxicity through PI3K/Akt-mediated mitochondrial apoptosis.

Concerns about chronic exposure to titanium dioxide nanoparticles (TiO2-NPs) have increased because of their widespread use in consumer products and subsequent environmental release. Previous studies have shown that TiO2-NPs exert neurotoxic effects and may contribute to Parkinson's disease (PD)-related neurodegenerati...

Zhi-Bing Zhang, Yanyan Fang, Shuang Chen et al. · Toxicology · 0 citations

Open access Aug 2026

Proteome stability and dynamic protein complex profiling identified EEF1A1 as a novel translation regulator of autophagy and mitophagy

This work integrates thermal proteome profiling with co-aggregation analysis to monitor protein thermal stability and complex assembly dynamics in response to two canonical inducers: Torin 1, which activates autophagy via mTOR inhibition, and CCCP, a mitochondrial uncoupler that triggers mitophagy.

Shuang Zhang, Ya Zeng, Feng-Ming Li et al. · Cell Communication and Signa... · 0 citations