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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jia-Jia Sun

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2 papers indexed here

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Open access Oct 2026

FOXM1-mediated transcriptional activation of CILP2 promotes malignant phenotypes and EMT-associated remodeling in clear cell renal cell carcinoma.

BACKGROUND Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cancer and remains associated with aggressive progression and poor clinical outcomes. Cartilage intermediate layer protein 2 (CILP2), an extracellular matrix-associated secreted protein, has been implicated in tumor-rela...

Jia-Jia Sun, Tong-Zhen Yan, Zi-Yuan Zhang et al. · 0 citations
Open access Sep 2026

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

ABSTRACT Acute kidney injury (AKI) is sustained by reciprocal amplification of oxidative stress, innate immune signaling, and maladaptive immune–parenchymal crosstalk. Here, we developed a lipid nanoparticle containing a ceria nanozyme and a STING‐targeting CasRx plasmid and functionalized it with D4F, an 18‐residue ap...

Wei-Bo Chen, Ming Li, Xue-Sheng Wang et al. · 0 citations

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