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Jia-Jie Niu

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Review Open access Sep 2026

Acupuncture Modulation of the Microbiota–Gut–Brain Axis in Major Depressive Disorder: Integrative Mechanisms, Emerging Evidence, and Future Therapeutic Perspectives

Preclinical evidence suggests that acupuncture may induce systemic anti-inflammatory responses, suppress NLRP3 inflammasome activation, restore HPA axis negative feedback, and repair the intestinal barrier, while also reshaping gut microbiota composition, promoting short-chain fatty acid synthesis, and regulating trypt...

Jing-Wen Zhang, Lin-Jing Wang, Shuai Shi et al. · 0 citations

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