Astragaloside IV Alleviates Transferrin Receptor 1-Mediated Ferroptosis in Diabetic Nephropathy
Background: Diabetic nephropathy (DN) is a leading cause of end-stage renal disease with limited therapeutic options. Astragaloside IV (AS-IV), a saponin monomer from Radix Astragali, has been reported to exert renoprotective effects; however, the underlying mechanism remains unclear. Network pharmacology identified tr...