Author

Jia-Lei Li

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Review Open access Sep 2026

Interplay between mitophagy, ferroptosis, and pyroptosis in acute pancreatitis: Regulatory mechanisms and therapeutic implications.

BACKGROUND With a very high death rate, acute pancreatitis (AP) is a frequent acute abdominal illness of the digestive system. It is challenging for the conventional notion of "trypsin self digestion" to adequately explain the molecular underpinnings of local inflammation that spreads across the body and the heterogene...

Jia-Lei Li, Shan-Qing Gao, Li Gao et al. · Tissue & Cell · 0 citations

Open access Sep 2026

Berberine Prevents and Reverses Gastric Spasmolytic Polypeptide-Expressing Metaplasia by Modulating M2 Macrophage Polarization

Findings provide preclinical evidence supporting berberine as a candidate therapeutic agent for SPEM by preventing and reversing tamoxifen-induced gastric SPEM by inhibiting M2 macrophage polarization and infiltration and regulating the JAK-STAT/NF-κB pathway and S100A6 expression.

Jia-Lei Li, Shi-Yi Ge, Xing-Xing Zhou et al. · International Journal of Mol... · 0 citations