Conventional pharmaceutical manufacturing is optimized for standardized fixed-dose products and offers limited flexibility for patients requiring individualized dosing, patient-acceptable dosage forms, or multidrug therapy. Semi-solid extrusion (SSE) 3D printing can process gels, pastes, suspensions, and other viscoela...
Bai-Yi Zeng, Xiao-Lu Han, Jia Li et al.· International journal of pha...· 0 citations
The developed population PK model for anakinra delivers the first critical understanding of small protein PK in premature neonates, establishing a foundation for evidence‐based dosing strategies to guide future prospective clinical trials.
Jia Li, D. Metz, Elys A. Green et al.· Clinical pharmacology and th...· 0 citations
Current available data are insufficient to validate the target exposure of anakinra across the full continuum spanning PK, PD, clinical outcomes, and safety, and this review highlights substantial gaps in the clinical PK/PD knowledge on anakinra, and model robustness.
Jia Li, Megan Clark, D. Metz et al.· Clinical Pharmacokinetics· 1 citation
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