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Author

Jia-Li Gao

2 papers indexed here

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Open access Aug 2026

Strategy for enhanced production of A40926B0 in Nonomuraea gerenzanensis using an efficient CRISPR/AsCas12f1 system

This work establishes a robust CRISPR editing tool for N. gerenzanensis and provides valuable engineering references for precursor-oriented strain improvement targeting lipoglycopeptide antibiotics, offering insights for the industrial scale production of A40926B0.

Xiao-Ru Wang, Hong-Mei Zhai, Dan-Dan Gu et al. · 0 citations
Open access Aug 2026

The flavonoid isoliquiritigenin promotes lifespan extension of Caenorhabditis elegans through the transcription factor DAF-16 and aquaporin-2

Aging is associated with the accumulation of oxidative damage. Isoliquiritigenin (ISL), a natural flavonoid, exhibits antioxidant properties, but its effect on lifespan and the underlying mechanisms remains incompletely understood. This study aimed to investigate whether ISL extends lifespan in Caenorhabditis elegans t...

Xuan Zhao, Limei Ren, Dandan Gu et al. · 0 citations

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