Systematic optimization of Komagataella phaffii (Pichia pastoris) for high-efficiency recombinant protein production: Advancements in strain engineering, fermentation optimization, and AI-driven technologies
Komagataella phaffii (formerly Pichia pastoris) has emerged as an indispensable eukaryotic expression host for the production of industrial enzymes, food proteins, and therapeutic proteins owing to its Generally Recognized as Safe (GRAS) status, efficient protein secretion capacity, eukaryotic post-translational modifi...