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Open access Aug 2026

Astrocytic HSP90AA1 Upregulation and Altered Synaptic Signaling in Parkinson’s Disease: Transcriptomic Screening and In Vivo Validation

Astrocytic upregulation of HSP90AA1 is associated with altered synapse-related intercellular communication patterns in the PD substantia nigra, potentially involving a predicted TP53 associated regulatory component.

Yiyuan Xu, Yanfeng Shi, Yan Li et al. · 0 citations