ABSTRACT Cancer remains a major global health burden despite recent advances in early diagnosis and novel therapeutics. The cytoskeleton is a dynamic filamentous network that controls cell morphology, motility, and intracellular trafficking; in normal cells, its activity is tightly regulated, whereas in cancer, it unde...
Jie Chen, Wen-Xin Yang, Yong-Han Song et al.· MedComm· 0 citations
It is elucidated that IL-23 upregulates METTL16, which in turn enhances PD-L1 expression and facilitates tumor immune escape, which establishes the IL-23/METTL16/PD-L1 axis as a novel regulatory pathway and potential therapeutic target in cancer immunotherapy.
Xue-Shan Pan, Yue Wang, Jing-Jing Luo et al.· American Journal of Cancer R...· 1 citation
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