Metabolic Engineering of Pichia pastoris for S‐Adenosylmethionine Overproduction via Transcriptomic‐Guided Energy Reallocation
S‐Adenosylmethionine (SAM) is a high‐value biomolecule with critical applications in nutraceuticals, pharmaceuticals, and health supplements. However, the detailed metabolic mechanism by which sodium citrate promotes SAM production in Pichia pastoris has not yet been elucidated. Here, a comprehensive time‐series transc...