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Author

Jia-Nan Ma

2 papers indexed here

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Oct 2026

Juglone induces GSDME-mediated pyroptosis by targeting HSP90α ATPase domain to promote STAT3 degradation in glioblastoma multiforme.

Glioblastoma (GBM) is a highly aggressive primary brain tumor with grim overall median survival, and its therapeutic efficacy is severely limited due to drug resistance. Therefore, developing effective and safe chemotherapy regimens is urgently required. Juglone, a natural bioactive constituent derived from traditional...

Hao Wu, Shuai Chen, Jia-Wen Li et al. · 0 citations
Open access Oct 2026

Early-onset colorectal cancer burden in China from 1990 to 2023: a systematic analysis based on the Global Burden of Disease Study 2023

Early-onset colorectal cancer (EOCRC) impairs the health of China’s working-age population and causes substantial socioeconomic costs. National long-term epidemiological data integrating trend segmentation, risk attribution and medium-term forecasting for domestic EOCRC remain insufficient. This study analysed Chin...

Hai-Jian Wei, Hao Wu, Shuai Wang et al. · 0 citations

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