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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jia-Nan Sun

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Sep 2026

Multifaceted Cross-Rational Modification of the α2,3-Sialyltransferase MsST for High-Efficiency Production of 3'-Sialyl-3-fucosyllactose via One-Pot Cascade Reaction.

3'-Sialyl-3-fucosyllactose (3'S3FL) is a representative fucose-containing sialylated human milk oligosaccharide with distinctive biological functions, but its in vitro synthesis is limited by the poor tolerance of α2,3-sialyltransferases toward fucosylated acceptors. Here, we report an engineered α2,3-sialyltransferase...

Yi-Fan Cao, Rui Chen, Tong-Yan Yin et al. · 0 citations
Sep 2026

Degradation Behavior and Mechanism of Agar Polysaccharides Induced by Hydrogen Peroxide: Structure Evolution and Bioactivity of Oligosaccharides

Although H2O2-mediated degradation efficiently yields bioactive oligosaccharides, the underlying mechanisms and structure–activity relationships (SARs) of agar polysaccharides remain elusive. Here, the H2O2 degradation profiles of agar (FA) and agarose (TA) were systematically compared using HRMS/MS and 2D NMR. FA pr...

Chao-Dong Yi, Jiang-Bin Shi, Bo-Lun Li et al. · 0 citations

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