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Aug 2026

A novel LncRNA TUG1/miR-30d/e-3p/SNAI2 ceRNA axis drives dermal fibrosis in systemic sclerosis via direct transcriptional activation of COL1A1.

Systemic sclerosis (SSc) is a severe autoimmune disease characterized by progressive dermal fibrosis, aberrant fibroblast activation, and excessive collagen deposition. Although noncoding RNA-mediated regulation has been increasingly implicated in fibrotic diseases, the role of the long noncoding RNA taurine-upregulate...

Ruixuan Zhu, Yangfan Xiao, Licong Liu et al. · 0 citations
Jul 2026

FABP5 attenuates pulmonary fibrosis by regulating lipid metabolism in type II alveolar epithelial cells.

It is found that FABP5 expression was significantly downregulated in AT2 cells from IPF patients and bleomycin-induced models, and FABP5 mitigated bleomycin-induced lung fibrosis by increasing global lipid and medium/long-chain fatty acid levels.

Hang Yin, Zhixiang Lei, Yuqi Mai et al. · 1 citation

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