Author

Jia-Ni Zhu

2 papers indexed here

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Open access Sep 2026

A Hypoxia Associated STC2 High Endothelial Subpopulation is Linked to Lipid Metabolic Reprogramming, Pathological Angiogenesis, and Immune Remodeling in Head and Neck Squamous Cell Carcinoma

Purpose Hypoxia drives malignant advancement and immune escape in HNSCC, but its cell‑type‑specific regulatory circuitry within the TME remains insufficiently elucidated. This study systematically characterizes hypoxia‑associated molecular programs and identifies core genes with relevance to prognosis and therapeutic r...

Kang-Ying Chen, Lu-Ying Qin, Zhi-Chao Liu et al. · International Journal of Gen... · 0 citations

Open access Aug 2026

Senescence-related immunosuppressive gene MFAP2 orchestrates stromal-immune crosstalk and immunotherapy resistance in gastric cancer

MFAP2 is a hub SRIG linking eCAFs, ECM remodeling, and immune escape in GC, which serves as a reliable prognostic and ICI resistance predictor and potential therapeutic target, providing a basis for precision therapy in GC.

Yi-Chan Hu, Liao-Xiang Zhu, Lijun Zhou et al. · BMC Cancer · 0 citations