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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jiaqi Liu

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Open access Sep 2026

ctDNA Release Heterogeneity in Luminal Breast Cancer Revealed by Single-Cell Multi-Omics Spatial Analysis

Backgroud Breast cancer is a leading cause of cancer-related mortality, and HR+/HER2− is the predominant subtype. Molecular pathology, including PIK3CA and ESR1 mutation, informs prognosis and treatment selection. Circulating tumor DNA (ctDNA) offers a non-invasive approach for cancer monitoring, but its clinical utili...

Heng-Yi Xu, Peng-Ming Pu, Bin-Liang Liu et al. · 0 citations
Open access Aug 2026

Generalizable cancer detection from ultra-low-pass WGS via deep contextual modeling of cfDNA sequences

Fragmentia-AI™ WGS, a mutation-calling-independent framework that uses a transformer-based multiple-instance learning architecture with sequential fine-tuning across tumor fraction (TF) strata to extract latent cancer-associated signals from ULP-WGS data, enables robust cancer detection and clinically meaningful risk s...

Yang Xu, Song Wang, Guo-Feng Sun et al. · 0 citations

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