Plasma proteomics is expanding across platforms and cohorts, and integrating these data for AI demands comparability at the protein level, not merely concordant associations1,2. Affinity and MS platforms use distinct probes (antibodies, aptamers, or peptides) and signal readouts, yielding contradictory cross-platform r...
PURPOSE
Primary stressors, such as frailty and caregiver burden, are predominant contributors to caregivers' depressive symptoms, but mechanisms underlying these relationships remain unknown.
METHOD
Path analysis was used to test whether mastery and competence mediate the effect of frailty and caregiver burden on dep...
Wen-Die Zhou, Zhe Wu, Cai-Xia Wang et al.· Research in Gerontological N...· 0 citations
OBJECTIVE
To investigate how the three frailty dimensions and caregiver burden impacted depressive symptoms among family caregivers of community-dwelling older adults with frailty via mastery and competence and the moderating role of coping.
METHODS
This cross-sectional study involved 464 caregivers of older adults w...
OBJECTIVES
To characterize long-term profiles of subjective memory ratings and examine their associations with cumulative, domain-specific, and individual social determinants of health (SDoH) among middle-aged and older adults.
METHODS
We analyzed six waves of the China Family Panel Studies (2012-2022) comprising 14,...
Xue Wang, Min Li, Wen-Die Zhou et al.· Archives of gerontology and...· 0 citations
Balance difficulty and memory problems may represent candidate symptom-prioritized targets for frailty management among older adults with chronic diseases and require validation in contemporary longitudinal cohorts and intervention studies.
Xue Wang, Li-Li Ji, Jia-Qi Yu et al.· Geriatric Nursing· 0 citations
The evidence suggests favourable but uncertain signals for selected proximal functional outcomes, with no clear benefit for distal clinical outcomes, given the limited evidence base, risk of bias, heterogeneity, imprecision, and very low certainty of evidence.
Xue Wang, Jia-Qi Yu, Wen-Die Zhou et al.· Ageing Research Reviews· 0 citations
DHI outcomes indicated generally good feasibility and adherence, though reach varied and safety reporting was incomplete, and further well-powered RCTs with standardized protocols and prespecified comparative designs are needed.
Min Li, Yi-Wei Gu, Jun-Ru Liao et al.· Research in Nursing and Heal...· 0 citations
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