Sep 2026
A dual-module ECAS complex couples transcription elongation and RNA processing.
Faithful gene expression requires coordination between RNA polymerase II elongation and co-transcriptional RNA processing, yet the chromatin-associated assemblies supporting this coupling remain incompletely defined. Using native chromatin proteomics in human cells, we identify ECAS (elongation complex associated with...
Ying Xiang, Honghong Wang, Zhinang Yin et al.
· Molecules and Cells · 0 citations