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Jia-Rui Wu

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Aug 2026

Dichloromethane Extract Is Responsible for the Evodiae Fructus induced Hepatotoxicity via PI3K-AKT/MAPK/p53/NF-κB Signaling Pathways through Integrated Network Pharmacology, Proteomic and Transcriptomic Analyses.

ETHNOPHARMACOLOGICAL RELEVANCE Tetradium ruticarpum (A.Juss.) T.G. Hartley (syn. Evodia rutaecarpa (Juss.) Benth., Rutaceae) , known as Wuzhuyu in Chinese and Evodiae Fructus (EF) in English, is a traditional Chinese medicine (TCM) with a history of over two thousand years. It was first documented in Shen Nong's Herbal...

Jia-Qi Li, Yihang Dai, Xiaolu Chen et al. · 0 citations
Aug 2026

Bufalin Induces Ferroptosis in Triple-Negative Breast Cancer via Inhibition of the NRF2/HO-1/GPX4 Pathway.

Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer characterized by poor prognosis and limited therapeutic options, remains a major clinical challenge. Bufalin, a principal bioactive component of Venenum Bufonis, exhibits potent anticancer activity against breast cancer. Nevertheless, th...

Ji-Ying Zhou, An-Xin Wang, M. Jin et al. · 0 citations

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