Open access
Jan 2026
Comparative Analysis of Antidepressant Mechanisms and Side Effects: Network Pharmacology and Molecular Docking Study of Amitriptyline, Mirtazapine, and Escitalopram for Treating Major Depressive Disorder
Background Amitriptyline, mirtazapine, and escitalopram are effective antidepressants for treating major depressive disorder (MDD). Our study aimed to use computational biology to understand the mechanisms for the similarities and differences in efficacies and side effects of these drugs. Methods Potential targets for...
C. Zhuo, Qiu-Yu Zhang, Hai-Tao Song et al.
· Depression and Anxiety · 0 citations